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IG Gene Rearrangement Detection Reagents (IGHV Mutation load Analysis) [PCR- DNA Sequencing based; require Sanger sequencing Platform]

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IG Gene Rearrangement Detection Reagents (IGHV Mutation load Analysis) [PCR- DNA Sequencing based; require Sanger sequencing Platform]

  • Revolutionize B Cell Neoplasm Characterization: Introducing Our Sanger Sequencing Technology

    Unlock the potential of precision medicine in the diagnosis and management of B cell neoplasms with our state-of-the-art Immunoglobulin (Ig) gene rearrangement and oncogenic translocation detection service. Harnessing the power of Sanger sequencing technology, we offer a comprehensive solution for characterizing B cell malignancies and stratifying patients based on distinct clinical and biological features.

    Why B Cell Neoplasm Characterization Matters

    B cell neoplasms encompass a spectrum of hematological malignancies with diverse clinical presentations and prognoses. Accurate characterization of these tumors is essential for tailoring individualized treatment strategies and predicting patient outcomes. Immunoglobulin gene rearrangements and oncogenic translocations are hallmark genetic alterations in B cell neoplasms, providing valuable insights into disease biology and therapeutic vulnerabilities.

    The Power of Sanger Sequencing Technology

    Our Sanger sequencing-based approach enables precise detection and characterization of Ig gene rearrangements and oncogenic translocations, allowing for comprehensive assessment of B cell neoplasm heterogeneity. With unparalleled sensitivity and specificity, Sanger sequencing offers a gold standard method for identifying clonal immunoglobulin gene rearrangements and aberrant translocations, guiding clinical decision-making and prognostic evaluation.

    Key Features of Our Service

    • Comprehensive Analysis: Detection of Ig gene rearrangements and oncogenic translocations for thorough characterization of B cell neoplasms.
    • High Sensitivity: Reliable detection of clonal populations and rare genetic events with exceptional sensitivity.
    • Clinical Relevance: Stratification of patients based on distinct genetic profiles to inform prognosis and treatment selection.
    • Expert Interpretation: Interpretation of sequencing data by experienced molecular pathologists to ensure accurate and clinically actionable results.
    • Customized Solutions: Tailored testing strategies to meet specific clinical and research needs, including panel design and result reporting options.

Empower Personalized Medicine

By leveraging our Sanger sequencing technology, clinicians and researchers can unlock the potential of precision medicine in the management of B cell neoplasms. From accurate diagnosis to targeted therapy selection and prognostic assessment, our comprehensive service empowers personalized treatment approaches, ultimately improving patient outcomes and quality of life.

Partner with Us Today

Join the forefront of B cell neoplasm characterization and personalized oncology care. Contact us today to learn more about our Immunoglobulin gene rearrangement and oncogenic translocation detection service and discover how it can revolutionize your approach to hematological malignancies. Together, let’s pave the way towards precision oncology and better outcomes for patients with B cell neoplasms.

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ORDER INFORMATION
REFPACKAGE
IGVHDS/WBB/2525 reactions
IGVHDS/WBB/100100 reactions
INTENDED USERFor research use only and NOT intended for in vitro diagnostics.
TECHNOLOGYConventional nested PCR amplification and Sanger DNA Sequencing
TYPE OF ANALYSISQualitative
TARGET SEQUENCEVariable region of the immunoglobulin heavy chain (IGHV) gene
ControlsPositive control
VALIDATED SPECIMANWhole blood
STORAGE-20 ± 5 °C
INSTRUMENTSCOMPATIBLE WITH A WIDE RANGE OF CONVENTIONAL PCR DEVICES AND ABI-DNA
CAPILLARY ELECTROPHORESIS SEQUENCING